김은희

김은희 교수

전공예방약학, 독성학
연락처 031-881-7179 ehkim@cha.ac.kr

학력

  • 서울대학교 농생물학과, 학사
  • 서울대학교 대학원 농생명공학부, 석사
  • 서울대학교 대학원 약학과, 박사(약품생화학전공)​

경력

  • Dartmouth College, Medical School, 박사후연구원
  • 가천대학교 이길여암당뇨연구원, 연구 조교수
  • (현)차 의과학대학교 약학대학, 조교수
  • (현)대한암예방학회지 편집위원
  • (현)대한약학회 정회원 (약품생화학 및 분자생물학 분과

논문

    주요연구내용
  • 한국인 호발 소화기질환 기전, 치료 및 예방전략 발굴 연구
  • 헬리코박터균 감염 유발 위질환 치료 및 예방 연구
  • 대사성 질환 관련 신약개발후보물질의 전임상 평가 및 기전 연구
  • 염증성 질환과 암성 질환과의 연관 규명을 기초로 염증제어를 통한 암예방 연구


  • 논문(최근 5년간. *교신저자 논문)
  • Cho JM, Kim KY, Ji SD and Kim EH* (2016) Protective effects of boiled and freeze-dried mature silkworm larval powder against diehtylnitrosamine-induced hepatotoxicity in mice. Journal of Cancer Prevention. 21(3): 173-181.
  • Kim DH, Park KW, Chae IG, Kundu J, Kim EH, Kundu JK, Chun KS (2016) Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells. Molecular Carcinogenesis. 55(6):1096-1110.
  • Park JM, Han YM, Jeong M, Kim EH, Ko WJ, Cho JY and Hahm KB (2015) Omega-3 polyunsaturated fatty acids as an angelus custos to rescue patients from NSAID-induced gastroduodenal damage. J. Gastroenterol., 50(6):614-625.
  • Park JM, Han YM, Kangwan N, Lee S, Jung MK, Kim EH*, and Hahm KB* (2014) S-allyl cysteine alleviates nonsteroidal anti-inflammatory drug-induced gastric mucosal damages by increasing cyclooxygenase-2 inhibition, heme oxygenase-1 induction, and histone deacetylation inhibition. Journal of Gastroenterology and Hepatology, 29 Suppl 4: 80-92.
  • Park JM, PArk SH, Hong KS, Han YM, Jang SH, Kim EH* and Hahm KB* (2014) Special licorice extracts containing lowered glycyrrhizin and enhanced licohchalcone A prevented Helicobacter pylori-initiated, salt diet-promoted gastric tumorigenesis. Helicobacter. 19(3):221-236.
  • Han YM, Ham KB, Park JM, Hong SP and Kim EH* (2014) Paradoxically augmented anti-tumerigenic action of proton pump inhibitor and gastric in APC/Min+ intestinal polyposis model. Neoplasia. 16(1):73-83.
  • Park JM, Kim YJ, Kim JS, Han YM, Kangwan N, Hahm KB, Kim TS, Kwon O and Kim EH* (2013) Anti-inflammatory and carbonic anhydrase restoring actions of yam powder (Dioscorea spp.) contribute to the prevention of cysteamine-induced duodenal ulcer in rat model. Nutr. Res. 33(8):677-685.
  • Kim EH, Bae JS, Hahm KB and Cha JY (2012) Endogenous synthesis of n-3 polyunsaturated fatty acis in fat-1 mice protects high fat diet induced non-alcoholic fatty liver disease. Biochem. Pharmacol. 84(10):1359-1365.
  • Kim EH, Deng C, Sporn MB, Williams CR, Royce D, Risingsong R, and Liby KT (2012) CDDO-methyl ester delays breast cancer development in BRCA1-mutated mice. Cancer Prev. Res. 5(1):89-97.

저서/역서/편서

  • 2012.07.03. 에스-알릴-엘-시스테인을 유효성분으로 포함하는 대장염 예방 또는 치료용 조성물 및 이를 포함하는 의약제제 (10-2012-00722080)