차 의과학대학교CHA University
 
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Nam Keun Kim

Nam Keun Kim

전공Molecular Genetics
연락처 031-881-7137 nkkim@cha.ac.kr

학력

  • 1979.3-1983.2 전북대학교 생물교육과 (이학사)
  • 1983.3-1985.2 서울대학교 자연대 동물학과 (이학석사)
  • 1985.3-1990.8 서울대학교 자연대 동물학과 (이학박사)

경력

  • 1991 – 1992 미국 국립오크리지 연구소 박사후연구원
  • 1992 – 1993 미국 텍사스대학 분자과학연구소 박사후연구원
  • 1993 – 1994 아주대학교 의과대학 연구강사
  • 1995 – 1997 차병원 여성의학연구소 유전학연구실장
  • 1997 – 현재 차 의과학대학교 생화학교실, 조교수, 부교수, 교수
  • 2011.9 – 현재 차 의과학대학교 의생명과학과 교수
  • 2012.3.1 – 현재 대검찰청 과학수사자문위원회위원 (DNA분과)
  • 2014.12 – 2017.2 차 의과학대학교 일반대학원 부원장
  • 2015.1 – 현재 한국유전학회 부회장


    • [수살실적]
  • 2011년 7월 5일, 제21회 과학기술우수논문상 수상
    수여기관: 한국과학기술단체총연합회.
  • 2014년 5월 31일, 대한생식의학회 최우수논문상 (머크-세로노 학술상)

논문

    [SCI급 국제학술논문]
  • Han IB, Kim OJ, Ahn JY, Oh D, Hong SY, Huh R, Chung SS, Kim NK. Association of methylenetetrahydrofolate reductase (MTHFR 677C>T and 1298A>C) polymorphisms and haplotypes with silent brain infarction and homocysteine levels in a Korean population. Yonsei Med J 2010; 51(2): 253-260. (PMID, 20191019; IF, 1.306)
  • Lee HH, Hong SH, Shin SJ, Ko JJ, Oh D, Kim NK. Association study of vascular endothelial growth factor polymorphisms with the risk of recurrent spontaneous abortion. Fertil Steril 2010; 93: 1244-1247. (PMID, 19131057; IF, 4.174)
  • Kim OJ, Kim UK, Oh SH, Cho YW, Oh KI, Oh D, Park YS, Kim NK. Association of endothelial nitric oxide synthase polymorphisms and haplotypes with ischemic stroke in Korean individuals with or without diabetes mellitus. Mol Med Rep 2010; 3: 509-513. (PMID, 21472271; IF, 1.170)
  • Song J, Kim OJ, Kim HS, Bae SJ, Hong SP, Oh D, Kim NK. Endothelial nitric oxide synthase gene polymorphisms and the risk of silent brain infarction. Int J Mol Med 2010; 31(6): 435-441. (PMID, 20372828; IF, 1.957)
  • Oh SH, Kim NK, Kim SH, Kim JK, Kim HS, Kim WC, Kim OJ. The prevalence and risk factor analysis of silent brain infarction in patients with first-ever ischemic stroke. J Neurol Sci 2010; 293: 97-101. (PMID, 20356606; IF, 2.243)
  • Bae J, Kim IJ, Hong SH, Sung JH, Lim SW, Cha DH, Cho YW, Oh D, Kim NK. Association of endothelial nitric oxide synthase polymorphisms with coronary artery disease in Korean individuals with or without diabetes mellitus. Exp Ther Med 2010; 1: 719-724. (PMID,22993595; IF, 0.344)
  • Shim SH, Yoon TK, Cha DH, Han WB, Choi DH, Kim NK. Endothelial nitric oxide synthase (eNOS) gene polymorphisms in spontaneously aborted embryos. Genes Genom 2010; 32(3): 105-110. (DOI,10.1007/s13258-010-0018-5; IF, 0.497)
  • Yim DJ, Kim OJ, An HJ, Kang H, Ahn DH, Hwang SG, Oh D, Kim NK. Polymorphisms of thymidylate synthase gene 5′- and 3-untranslated region and risk of gastric cancer in Koreans. Anticancer Res 2010; 30(6): 2325-2330. (PMID, 20651387; IF, 1.713)
  • Shin SJ, Lee HH, Cha SH, Kim JH, Shim SH, Choi DH, Kim NK. Endothelial nitric oxide synthase gene polymorphisms (-786T>C, 4a4b, 894G>T) and haplotypes in Korean patients with recurrent spontaneous abortion. Eur J Obstet Gynecol Reprod Biol 2010; 152(1): 64-67. (PMID, 20728041; IF, 1.843)
  • Kang SY, Lee SJ, Hong SH, Chung YK, Oh HS, Kim SW, Yim DJ, Kim NK. Polymorphisms of 5,10-methylenetetrahydrofolate reductase and thymidylate synthase in squamous cell carcinoma and basal cell carcinoma of the skin. Mol Med Rep 2010; 3(5): 741-747. (PMID, 21472308; IF, 1.170)
  • Kim OJ, Lee JH, Choi JK, Oh SH, Hong SH, Oh D, Kim NK. Association between tumor necrosis factor-alpha (-308G>A and -238G>A) polymorphisms and homocysteine levels in patients with ischemic strokes and silent brain infarctions. Cerebrovasc Dis 2010; 30(5): 483-490. (PMID, 20798494; IF, 2.814)
  • Kim JW, Lee JH, Hong SH, Yim DJ, An HJ, Chong SY, Oh D, Kim NK. Combination of polymorphisms between MTHFR and TS gene modulates survival after 5-fluorouracil- based therapy in colorectal cancer patients. Genes Genom 2010; 32(5): 469-475. ( DOI, 10.1007/s13258-010-0045-2; IF, 0.497)
  • Jeon S, Won HJ, Kim YS, Lyu SW, Seok HH, Kim NK, Lee WS, Shim SH, Yoon TK, Choi Y. Novel single-nucleotide polymorphisms of LHX8 gene in Korean women with premature ovarian insufficiency. Genes Genom 2010; 32(5): 397-400. (DOI, 10.1007/s13258-010-0008-7; IF, 0.497)
  • Chung YS, Hong SH, Shin DE, Lee JH, Min KT, Ahn JY, Kim NK. Association of vascular endothelial growth factor gene polymorphisms with osteoporotic vertebral compression fractures in postmenopausal women. Genes Genom 2010; 32(6): 499-505. (DOI, 10.1007/s13258-010-0013-x; IF, 0.497)
  • Kim JW, Park HM, Choi YK, Chong SY, Oh D, Kim NK. Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients. Oncol Rep 2011; 25: 167-172. (PMID, 21109973; IF, 1.686)
  • Kim NK, Shin DA, Han IB, Yoo EH, Kim SH, Chung SS. Association study of an aggrecan gene polymorphism with the risk of intervertebral disc degeneration. Acta Neurochir 2010; 153:129-133. (PMID, 20936487; IF, 1.329).
  • Choi BO, Kim NK, Park SW, Hyun YS, Jeon HJ, Hwang JH, Chung KW. Inheritance of Charcot-Marie-Tooth disease 1A with rare nonrecurrent genomic rearrangement. Neurogenetics 2011; 12:51-58. (PMID, 21193943; IF, 3.488)
  • Oh SH, Kim NK, Kim HS, Kim WC, Kim OJ. Plasma total homocysteine and methylenetetrahydrofolate reductase 677C>T polymorphism do not contribute to distribution of cervico-cerebral atherosclerosis. Eur J Neurol 2011;18(3):491-6. (PMID, 20825473; IF, 3.765)
  • Kim TG, Kim NK, Baek MJ, Huh R, Chung SS, Choi JU, Yu SY. The relationships between endothelial nitric oxide synthase polymorphisms and the formation of intracranial aneurysms in the Korean population. Neurosurg Focus 2011;30(6):E23. (PMID, 21631225; IF, 2.348)
  • Kim MH, Moon JS, Park SY, An SA, Kim OJ, Kim NK, Oh SH. Different risk factor profiles between silent brain infarction and symptomatic lacunar infarction. Eur Neurol 2011;65(5):250-256. (PMID, 21464570; IF, 1.76)
  • Choi YS, Choi JK, Kim JW, Min KT, Kwon YD, Jang MJ, Chong SY, Oh D, Cho YK, Hong .SH, Kim NK. Association of the vascular endothelial growth factor (VEGF -1154G>A) polymorphism in patients with colorectal cancer. Genes Genom 2011; 33(2):133-138. (DOI, 10.1007/s13258-010-0152-0; IF, 0.453)
  • Jeon YJ, Choi YS, Rah HC, Choi Y, Yoon TK, Choi DH, Kim NK. The reduced folate carrier-1 (RFC1 696T>C) polymorphism is associated with spontaneously aborted embryos in Koreans. Genes Genom 2011;33:223-228. ( DOI, 10.1007/s13258-011-0016-2; IF, 0.453)
  • Choi HS, Cheong HI, Kim NK, Oh D, Park HW. ADAMTS13 gene mutations in children with hemolytic uremic syndrome. Yonsei Med J 2011; 52(3):530-534. (PMID, 21488199; IF, 1.02)
  • Choi YS, Kwon H, Kim JH, Shin JE, Choi Y, Yoon TK, Choi DH, Kim NK. Haplotype-based association of ACE I/D, AT1R 1166A>C, and AGT M235T polymorphisms in renin-angiotensin-aldosterone system genes in Korean women with idiopathic recurrent spontaneous abortions. Eur J Obstet Gynecol Reprod Biol 2011; 158(2):225-228. (PMID, 21636204; IF, 1.764)
  • Park YS, Min KT, Kim TG, Lee YH, Cheong HJ, Yeom IS, Choi JU, Kim DS, Kim NK. Age-specific eNOS polymorphisms in moyamoya disease. Childs Nerv Syst 2011;27(11):1919-1926. (IF, 1.314; 2011.11.01; 2010-0023851). Park YS, Kim NK. eNOS polymorphisms in moyamoya disease. Childs Nerv Syst 2011;27:1859. (PMID, 21833724; IF, 1.314)
  • Oh SH, Min KT, Jeon YJ, Kim MH, Moon JS, Kim HS, Kim WC, Kim OJ, Park EK, Kim NK. Association between kinase insert domain-containing receptor gene polymorphism and haplotypes and ischemic stroke. J Neurol Sci 2011;308:62-66. (PMID, 21705026; IF, 2.167).
  • Kim OJ, Hong SH, Oh SH, Kim TG, Min KT, Oh D, Kim NK. Association between VEGF polymorphisms and homocysteine levels in patients with ischemic stroke and silent brain infarction. Stroke 2011;42(9):2393-2402 (PMID, 21737794; IF, 5.756)
  • Jang MJ, Kim JW, Min KT, Jeon YJ, Oh D, Kim NK. Prognostic significance of microRNA polymorphisms in patients with surgically resected colorectal cancer. Exp Ther Med 2011;2(6):1127-1132. (PMID, 22977632 IF, 0.206)
  • Jeon YJ, Choi Y, Shim SH, Choi YS, Ko JJ, Yoon TK, Cha SH, Kim NK. Vascular endothelial growth factor gene polymorphisms in Korean patients with premature ovarian failure. Eur J Obstet Gynecol Reprod Biol 2011;159(1):138-142. (PMID, 21831507; IF, 1.764)
  • Jeon YJ, Kim JH, Rah HC, Kim SY, Yoon TK, Choi DH, Cha SH, Shim SH, and Kim NK. Vascular endothelial growth factor gene polymorphisms in spontaneously aborted fetuses. Am J Reprod Immunol 2011;66(6):544-553. (PMID, 21902756; IF, 2.451)
  • Jeon YJ, Choi YS, Rah H, Kim SY, Choi DH, Cha SH, Shin JE, Shim SH, Lee WS, Kim NK. Association study of microRNA polymorphisms with risk of idiopathic recurrent spontaneous abortion in Korean women. Gene 2012;494(2):168-173 (PMID, 22222140; IF, 2.266)
  • Rah HC, Choi YS, Jeon YJ, Choi Y, Cha SH, Choi DH, Ko JJ, Shim SH, Kim NK. Solute carrier family 19, member 1 (SLC19A1) polymorphisms (-43T>C, 80G>A, 696C>T) and haplotypes in idiopathic recurrent spontaneous abortion in a Korean population. Reprod Sci 2012;19(5):513-519 (PMID, 22344739; IF, 2.586; )
  • Han IB, Kim OJ, Ropper AE, Kim HS, Cho YK, Teng YD, Kim NK. Association between kinase insert domain-containing receptor (KDR) gene polymorphisms and silent brain infarction. J Neurol Sci 2012;318(1-2):85-89. (PMID, 22520092IF, 2.167)
  • Kim WH, Min KT, Jeon YJ, Kwon CI, Ko KH, Park PW, Hong SP, Rim KS, Kwon SW, Hwang SG, Kim NK. Association study of microRNA polymorphisms with hepatocellular carcinoma in Korean population. Gene 2012;504(1):92-97 (PMID, 22583825; IF, 2.266)
  • Park YS, Jeon YJ, Lee BE, Kim TG, Choi JU, Kim DS, Kim NK. Association of the miR-146aC>G, miR-196a2C>T and miR-499A>G polymorphisms with moyamoya disease in the Korean population. Neurosci Lett 2012;521(1):71-75 (PMID, 22659075; IF, 2.055)
  • Chung YS, Jeon YJ, Shin DE, Min KT, Shin YS, Won KS, Cho JH, Koh YC, Hong SH, Kim NK. Methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TS) polymorphisms with osteoporotic vertebral compression fracture (OVCF) in post- menopausal Korean women. Genes Genom 2012;34(3):257-263 (DOI, 10.1007/s13258-011-0202-2; IF, 0.453).
  • Jang MJ, Oh J, Oh D, Chong SY, Jeon YJ, Min KT, Park S, Yun-Choi HS, Kim NK. Polymorphisms of platelet ADP receptor P2RY12 in the risk of venous thromboembolism in the Korean population. Clin Appl Thromb Hemost 2012;18(4):416-420. (PMID, 22275393, IF, 1.476; )
  • Min KT, Kim JW, Jeon YJ, Jang MJ, Chong SY, Oh D, Kim NK. Association of the miR-146aC>G, 149C>T, 196a2C>T, and 499A>G polymorphisms with colorectal cancer in the Korean population. Mol Carcinog 2012;51(S1):E65-73. (PMID, 22161766; IF, 3.162)
  • Rah HC, Jeon YJ, Choi Y, Shim SH, Ko JJ, Yoon TK, Cha SH, Kim NK. Association between kinase insert domain-containing receptor (KDR) polymorphisms (-604T>C, 1192G>A, 1719A>T) and premature ovarian failure in Korean women. Menopause 2012;19(9):1037-1042. (PMID, 22510937; IF, 3.758)
  • Rah HC, Jeon YJ, Choi Y, Shim SH, Yoon TK, Choi DH, Cha SH, Kim NK. Association of methylenetetrahydrofolate reductase (MTHFR 677C>T) and thymidylate synthase (TSER and TS 1494del6) polymorphisms with premature ovarian failure in Korean women. Menopause 2012;19(11):1260-1266. (PMID, 22713864; IF, 3.758)
  • Kim SY, Jeon YJ, Oh SH, Kim HS, Kim OJ, Oh D, Jeung M, Shin BS, Park YS, Kim NK. Association of kinase insert domain receptor (KDR 604, 1192, and 1719) polymorphisms with cerebral white matter lesions. Genes Genom 2012;34(5):485-492. (DOI, 10.1007/s13258-012-0069-x; IF, 0.453)
  • Jeon YJ, Kim SY, Rah H, Choi DH, Cha SH, Yoon TK, Lee WS, Shim SH, and Kim NK. Association of the miR-146aC>G, miR-149T>C, miR-196a2T>C, and miR-499A>G polymorphisms with risk of spontaneously aborted fetuses. Am J Reprod Immunol 2012;68(5):408-417. (PMID, 22882355; IF, 3.05).
  • Kim JH, Jeon YJ, Rah HC, Lee BE, Choi DH, Lee WS, Kim NK. Tumor necrosis factor-α promoter polymorphisms are associated with idiopathic primary ovarian insufficiency in Korean women. Fertil Steril 2012;98(5):1260-1265. (PMID, 22884017; IF, 3.564)
  • Park YS, Jeon YJ, Kim HS, Chae KY, Oh SH, Han IB, Kim HS, Kim WC, Kim OJ, Kim TG, Choi JU, Kim DS, Kim NK. The role of VEGF and KDR polymorphisms in moyamoya disease and collateral revascularization. PLoS One 2012;7(10):e47158. (PMID 23077562; IF, 4.092)
  • Oh SH, Min KT, Jeon YJ, Kim MH, Kim OJ, Shin BS, Oh D, Kim NK. Association between common genetic variants of 2A-, 2B-, and 2C-adrenergic receptors and ischemic stroke. Clin Neurol Neurosurg 2013;115(1):26-31. (PMID, 22560155; IF, 1.234).
  • Rah HC, Jeon YJ, Shim SH, Cha SH, Choi DH, Kwon H, Kim JH, Shin JE, Kim NK. Association of miR-146aC>G, miR-196a2T>C, and miR-499A>G polymorphisms with risk of premature ovarian failure in Korean women. Reprod Sci 2013;20(1):60-68. (PMID, 22872486; IF, 2.064).
  • Jang MJ, Jeon YJ, Kim JW, Chong SY, Hong SP, Oh D, Cho YK, Chung KW, Kim NK. Association of eNOS polymorphisms (-786T>C, 4a4b, 894G>T) with colorectal cancer susceptibility in the Korean population. Gene 2013;512(2):275-281. (PMID, 23137631; IF, 2.196).
  • Park SY, An SA, Lee HB, Kim Y, Kim NK, Kim SH, Kim OJ, Oh SH. Different impact of hyperhomocysteinemia on cerebral small vessel ischemia and cervico- cerebral atherosclerosis in non-stroke individuals. Thromb Res 2013;131(1):e12-e16. (PMID, 23218488; IF, 3.133)
  • Kim OJ, Hong SH, Jeon YJ, Oh SH, Kim HS, Park YS, Kim EJ, Kim NK. Gene–environment interactions between methylenetetrahydrofolate reductase (MTHFR) 677C>T and metabolic syndrome for the prevalence of ischemic stroke in Koreans. Neurosci Lett 2013;533:11-16. (PMID, 23201630; IF, 2.026)
  • Rah H, Jeon YJ, Lee WS, Jung YW, Choi DH, Kwon H, Kim JH, Shin JE, Kim NK. Association of nitric oxide synthase gene polymorphisms (-786T>C, 4a4b, 894G>T) with primary ovarian insufficiency in Korean women. Maturitas 2013;74(2):160-165. (PMID, 2317675;8 IF, 2.844)
  • Jeon YJ, Kim OJ, Kim SY, Oh SH, Oh D, Kim OJ, Kim NK. Association of the miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms with ischemic stroke and SBI risk. Arterioscler Thromb Vasc Biol 2013;33(2):420-430. (PMID, 23202363; IF, 6.338)
  • Han IB, Ropper AE, Jeon YJ, Park HS, Teng YD, Kuh SU, Kim NK. Association of transforming growth factor-beta 1 gene polymorphism with genetic susceptibility to ossification of the posterior longitudinal ligament in Korean patients. Genet Mol Res 2013;12(4):4807-4816. (PMID, 23479171; IF, 0.994)
  • Jung YW, Jeon YJ, Park HM, Lee BE, Rah H, Lee WS, Yoon TK, Kim NK. Association between polymorphisms in the renin-angiotensin system genes and primary ovarian insufficiency in Korean women. Menopause 2013;20(5):561-567. (PMID, 23615648; IF, 3.163).
  • Lee BE, Jeon YJ, Shin JE, Kim JH, Choi DH, Jung YW, Shim SH, Lee WS, Kim NK. Tumor necrosis factor-α gene polymorphisms in Korean patients with recurrent spontaneous abortion. Reprod Sci 2013;20(4):408-413. (PMID, 23202728; IF, 2.064)
  • An SA, Kim J, Kim OJ, Kim JK, Kim NK, Song J, Oh SH. Limited clinical value of multiple blood markers in the diagnosis of ischemic stroke. Clin Biochem 2013;46(9):710-715. (PMID, 23462697; IF, 2.45).
  • Rah H, Jeon YJ, Lee BE, Choi DH, Yoon TK, Lee WS, Kim NK. Association of kinase insert domain-containing receptor (KDR) gene polymorphisms with idiopathic recurrent spontaneous abortion in Korean women. Fertil Steril 2013;99(3):753-60.e8. (PMID, 23158831; IF, 4.174)
  • Kim JH, Jeon YJ, Lee BE, Kang HJ, Shin JE, Choi DH, Lee WS, Kim NK. Association of methionine synthase and thymidylate synthase genetic polymorphisms with idiopathic recurrent pregnancy loss. Fertil Steril 2013;99(6):1674-80. (PMID, 23415967; IF, 4.174)
  • Son MS, Jang MJ, Jeon YJ, Kim WH, Kwon CI, Ko KH, Park PW, Hong SP, Rim KS, Kwon SW, Hwang SG, Kim NK. Promoter polymorphisms of pri-miR-34b/c are associated with hepatocellular carcinoma. Gene 2013;524:156-60. (PMID, 23632240; IF, 2.196)
  • Jang MJ, Jeon YJ, Choi WI, Choi YS, Kim SY, Chong SY, Doyeun Oh, Kim NK. The 677C>T mutation of the methylenetetrahydrofolate reductase gene increases the risk for venous thromboembolism in Koreans: a meta-analysis from Asian population. Clin Appl Thromb Hemost 2013;19(3):309-314 (PMID, 22327825; IF, 1.016)
  • Han IB, Ropper AE, Shin DE, Park YS, Shin DA, Jeon YJ, Park HM, Teng YD, Kim NK. Association between VEGF and eNOS gene polymorphisms and lumbar disc degeneration in a young Korean population. Genet Mol Res 2013;12(3):2294- 2305. (PMID, 22884772; IF, 0.994)
  • Jeon YJ, Kim JH, Leee, BE, Rha H, Shin JE, Kang H, Choi DH, Yoon TK, Lee WS, Shim SH, Kim NK. Association between polymorphisms in the renin-angiotensin system genes and prevalence of spontaneously aborted fetuses. Am J Reprod Immunol 2013;70(3):238- 245 (PMID, 23480300; IF, 3.317)
  • Chin DK, Han IB, Ropper AE, Jeon YJ, Kim DH, Kim YS, Teng YD, Kim NK, Kuh SU. Association of VKORC1 -1639G>A Polymorphism with susceptibility to ossification of the posterior longitudinal ligament of the spine: a Korean study. Acta Neurochir 2013;155(10):1937-1942. (PMID, 23732872; IF, 1.52).
  • Rah H, Jeon YJ, Lee BE, Kim JO, Shim SH, Lee WS, Choi DH, Kim JH, Kim NK. Association of polymorphisms in microRNA machinery genes (DROSHA, DICER1, RAN, and XPO5) with risk for idiopathic primary ovarian insufficiency in Korean women. Menopause 2013;20(10): 1067-1073. (PMID, 23549446; IF, 3.163)
  • Jeon YJ, Kim YR, Choi YS, Lee BE, Kim JH, Shin JE, Rah H, Cha SH, Lee WS, Kim NK. Genetic association of five plasminogen activator inhibitor-1 (PAI-1) polymorphisms and idiopathic recurrent pregnancy loss in Korean women. Thromb Haemost 2013;110(4):742-750. (PMID, 23903286; IF, 6.094)
  • Ahn DH, Rah H, Choi YK, Jeon YJ, Min KT, Kwack K, Hong SP, Hwang SG, Kim NK. Association of the miR-146aC>G, miR-149T>C, miR-196a2T>C, and miR-499A>G polymorphisms with gastric cancer risk and survival in the Korean population. Mol Carcinog 2013;52(S1):E39-E51. (PMID, 23001871; IF, 4.269).
  • Jang MJ, Jeon YJ, Kim JW, Cho YK, Lee SK, Hwang SG, Oh D, Kim NK. Association of VEGF and KDR single nucleotide polymorphisms with colorectal cancer susceptibility in Koreans. Mol Carcinog 2013;52(S1):E60-E69. (PMID, 23169005; IF, 4.269).
  • Jang MJ, Kim JW, Jeon YJ, Chong SY, Oh D, Kim NK. Prognostic significance of vascular endothelial growth factor gene polymorphisms in patients with colorectal cancer. Int J Clin Oncol 2013;18(6):1032-41. (PMID, 23132736; IF, 1.727).
  • Jang MJ, Kim JW, Jeon YJ, Chong SY, Hong SP, Hwang SG, Oh D, Cho YK, Ji YG, Kim NK. Polymorphisms of folate metabolism-related genes and survival of patients with colorectal cancer in the Korean population. Gene 2014;533(2):558-564. (PMID, 24100087; IF, 2.082)
  • Oh JS, Kim JW, Lee BE, Jang MJ, Chong SY, Park PW, Hwang SG, Oh D, Kim NK. Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer. Oncol Rep 2014;31(2):995-1002. (PMID, 24337371; IF, 2.191)
  • Rah H, Jeon YJ, Ko JJ, Kim JH, Kim YR, Cha SH, Choi Y, Lee WS, Kim NK. Association of inhibin α gene promoter polymorphisms with risk of idiopathic primary ovarian insufficiency in Korean women. Maturitas 2014;77(2):163-167. (PMID, 24269065; IF, 2.861)
  • Jeon YJ, Lee BE, Cha SH, Kim YR, Moon MJ, Oh D, Lee WS, Kim NK. Association of five common polymorphisms in the plasminogen activator inhibitor-1 gene with primary ovarian insufficiency. Fertil Steril 2014;101(3):825-832.e1. (PMID, 24355042; IF, 4.295)
  • Yadav BK, Oh SY, Kim NK, Shin BS. Association of rs2075575 and rs9951307 polymorphisms of AQP-4 gene with leukoaraiosis. J Stroke Cerebrovasc Dis 2014; 23(5):1159-1206. (PMID, 24582793; IF, 1.993)
  • Kim JO, Jeon YJ, Kim OJ, Oh SH, Kim HS, Shin BS, Oh D, Cho YK, Kim NK. Association between common genetic variants of α2A-, α2B-, and α2C-adrenergic receptors and the risk of silent brain infarction. Mol Med Rep 2014;9(6):2459- 2466. (PMID, 22560155; IF, 1.484)
  • Jung YW, Jeon YJ, Rah H, Kim JH, Shin JE, Kim YR, Cha SH, Kim NK. Genetic variants in microRNA machinery genes are associated with idiopathic recurrent pregnancy loss risk. PLoS One 2014;9(4):e95803. (PMID, 24769857; IF, 3.534)
  • Kim JO, Lee WS, Lee BE, Jeon YJ, Kim YR, Jung SH, Chang SW, Kim NK. Interleukin-1β -511T>C genetic variant contributes to recurrent pregnancy loss risk and peripheral natural killer cell proportion. Fertil Steril 2014; 102(1): 206-212.e5. (PMID, 24784935; IF, 4.295)
  • Kim HS, Lee BE, Jeon YJ, Rah H, Lee WS, Shin JE, Choi DH, Kim NK. Transcobalamin II (TCN2 67A>G and TCN2 776C>G) and Transcobalamin II Receptor (TCblR 1104C>T) Polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion. Am J Reprod Immunol 2014;72(3):337-346. (PMID, 24750446; IF, 2.668)
  • Kang MK, Kim OJ, Jeon YJ, Kim HS, Oh SH, Kim JK, Han IB, Kim EJ, Hwang TS, Kim NK. Interplay between polymorphisms in the endothelial nitric oxide synthase (eNOS) gene and metabolic syndrome in determining the risk of ischemic stroke in Koreans. J Neurol Sci 2014;344(1-2):55-59. (PMID, 24976532; IF, 2.262).
  • Park YS, Jeon YJ, Kim HS, Han IB, Choi JU, Kim DS, Kim NK. The roles of methylenetetrahydrofolate reductase 677C>T and 1298A>C polymorphisms in moyamoya disease patients. Childs Nerv Sys 2014;30(10):1687-1695. (PMID, 25098357; IF, 1.163).
  • Lee HB, Kim Y, Yoo H, Lee JM, Kim YK, Kim NK, Kim JK, Oh SH. Blood genomic profiling in extracranial- and intracranial atherosclerosis in ischemic stroke patients. Thromb Res 2014;134(3):686-92. (PMID, 25042724; IF, 2.427)
  • Kim RJ, Bae E, Hong JY, Kim NK, Ahn HJ, Oh JJ, Park DS. PTEN loss-mediated Akt activation increases the properties of cancer stem-like cell populations in prostate cancer. Oncology 2014;87(5):270-279. (PMID, 25139413; IF, 2.613)
  • Kim Y, Kim YK, Kim NK, Kim SH, Kim OJ, Oh SH. Circulating matrix metalloproteinase-9 level is associated with cerebral white matter hyperintensities in non-stroke individuals. Eur Neurol 2014; 72:234-40. (PMID, 25248031; IF, 1.362)
  • Park YS, Jeon YJ, Kim HS, Han IB, Oh SH, Kim DS, Kim NK. The GC+CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2 is genetic predisposing factors for prevalence of moyamoya disease. BMC Neurol 2014;14(1):180. (PMID, 25280484; IF, 2.486)
  • Jeon YJ, Kim JW, Park HM, Jang HG, Kim JO, Oh J, Chong SY, Kwon SW, Kim EJ, Oh D, Kim NK. Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans. BMC Cancer 2014;14(1):881. (PMID, 25423914; IF, 3.317)
  • Kim YR, Jeon YJ, Kim HS, Kim JO, Moon MJ, Ahn EH, Lee WS, Kim NK. Association study of five functional polymorphisms in matrix metalloproteinase-2, -3, and -9 genes with risk of primary ovarian insufficiency in Korean women. Maturitas 2015;80(2):192-197. (PMID, 25482733; IF, 2.861)
  • Cho Y, Kim JO, Lee JH, Park HM, Jeon YJ, Oh SH, Bae J, Park YS, Kim OJ, Kim NK. Association of reduced folate carrier-1 (RFC-1) polymorphisms with ischemic stroke and silent brain infarction. PLoS One 2015;10(2):e0115295. (PMID, 25659099; IF, 3.534)
  • Rah H, Kim HS, Cha SH, Kim YR, Lee WS, Ko JJ, Kim NK. Association of breast cancer-related microRNA polymorphisms with idiopathic primary ovarian insufficiency. Menopause 2015;22(4):437-443. (PMID, 25203895; IF, 2.807).
  • Cho YK, Kim OJ, Park HM, Jeon YJ, Oh SH, Kim JK, Oh D, Shin BS, Kim NK. Predisposing roles of paraoxonase-1 genetic variants in Korean ischemic stroke patients. Gene Genom 2015;37(7):579-586. (DOI, 10.1007/s13258-015-0287-0; IF, 0.565)
  • Jeon YJ, Kim JW, Park HM, Kim JO, Jang HG, Oh J, Hwang SG, Kwon SW, Oh D, Nam Kim NK. Genetic variants in 3’-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Korean. Sci Rep 2015;5:11006. (DOI, 10.1038/srep11006; IF, 5.078)
  • Cho SH, Ko JJ, Kim JO, Jeon YJ, Yoo JK, Oh J, Oh D, Kim JW, Kim NK. 3’ UTR polymorphisms in the miRNA machinery genes DROSHA, DICER1, RAN, and XPO5 are associated with colorectal cancer risk in a Korean population. PLoS One 2015;10(7):e0131125. doi: 10.1371/journal.pone.0131125. (IF, 3.234-2014)
  • Jung J, Kim NK, Park S, Shin HJ, Hwang SG, Kim N. Inhibitory effect of Phyllanthus urinaria L. extract on the replication of lamivudine-resistant hepatitis B virus in vitro. BMC Complement Altern Med 2015;15:255. doi: 10.1186/s12906 –015-0792-3. (IF, 2.02-2014)
  • Kim B, Kim MK, Kim SW, Kim KM, Kim HS, An HJ, Kim JO, Choi TK, Kim NK, Lee SH. Association of human microRNAs miR-22 and miR-491 polymorphisms with panic disorder with or without agoraphobia in a Korean population. J Affect Disord 2015;188:118-126. (IF, 3.383-2014; 공동교신저자)
  • Sung JH, Lee BE, Kim JO, Jeon YJ, Kim SH, Lim SW, Moon JY, Cha DH, Kim OJ, Kim IJ, Kim NK. Association between eNOS polymorphisms and coronary artery disease in the Korean population: a meta-analysis. Genet Mol Res 2015;14(4):16508-16520. (IF, 0.775-2014)
  • Shin SP, Kim NK, Kim JH, Lee JH, Kim JO, Cho SH, Park H, Kim MN, Rim KS, Hwang SG. Association between hepatocellular carcinoma and tumor necrosis factor alpha polymorphisms in South Korea. World J Gastroenterol 2015;21(46): 13064-13072. doi:10.3748/wjg.v21.i46.13064. (IF, 2.369-2014)
  • Jung YW, Kim JO, Rah H, Kim JH, Kim YR, Lee Y, Lee WS, Kim NK. Genetic variants of vascular endothelial growth factor are associated with recurrent implantation failure in Korean women. Reprod Biomed Online 2016;32(2):190-196. (IF, 3.105-2014)
  • Jang H, Lee OH, Lee Y, Yoon H, Chang EM, Park M, Lee JW, Hong K, Kim JO, Kim NK, Ko JJ, Lee DR, Yoon TK, Lee WS, Choi Y. Melatonin prevents cisplatin-induced primordial follicle loss via suppression of PTEN/AKT/FOXO3a pathway activation in the mouse ovary. J Pineal Res 2016;60:336-347. (IF, 9.6-2014)
  • Jang HG, Choi Y, Kim JO, Jeon YJ, Rah HC, Kim JH, Lee WS, Kim NK. Tumor necrosis factor-alpha (-863C>A, -857C>A, +488G>A) polymorphisms are associated with idiopathic recurrent pregnancy loss in Korean women. Hum Immunol 2016;77(6):506-511. (IF, 2.138-2014)
  • Cho SH, Chung KW, Kim JO, Jang HG, Shin JS, Yoo JK, Choi Y, Ko JJ, Kim JH, Lee WS, Kim NK. Association of the miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms with the risk of repeated implantation failure in Korean women. Eur J Obstet Gynecol Reprod Biol 2016;202:14-19. (IF, 1.695-2014)
  • Choi GH, Ko KH, Kim JO, Kim JK, Oh SH, Han IB, Cho KG, Ok Kim OJ, Bae J, Kim NK. Association study of miR-34a, miR-130a, miR-150, and miR-155 polymorphisms with ischemic stroke risk. Int J Mol Med 2016;38(1):345-356. (IF, 2.088-2014)
  • Sung JH, Kim SH, Yang WI, Kim WJ, Moon JY, Kim IJ, Cha DH, Cho SY, Kim JO, Kim KA, Kim OJ, Lim SW, Kim NK. MicroRNA polymorphisms (miR-146a, miR-149, miR-196a2, miR-499) are associated with the risk for coronary artery diseases in a Korean population. Mol Med Rep 2016; in press (IF, 1.554-2014)
  • Lee JY, Kim NK, Cho YW, LEW H. Association between methylenetetrahydro- folate reductase (MTHFR) polymorphisms and susceptibility to Graves’ ophthalmopathy. Mol Med Rep 2016; in press (IF, 1.554-2014)

    • [비 SCI급 국제학술 논문 (8편)]
  • Kang BS, Ahn DH, Kim NK, Kim JW. Relationship between metabolic syndrome and MTHFR polymorphism in colorectal cancer. J Kor Soc Coloprotol 2011;27(2): 78-82. (PMID, 21602966)
  • Kim MH, An SA, Lee HB, Choo SW, Kim NK, Kim WC, Kim OJ, Oh SH. Association between single nucleotide polymorphisms of a2A-, a2B-, and a2C- adrenergic receptor genes and risk of cerebral white matter lesion. Korean J Stroke 2011;13(2):66-73.
  • Chang HJ, Kim NK, Jeon YJ, Kim JW. The relationship between the progression of colorectal cancer and microRNA polymorphisms. Korean J Clin Oncol 2011;7(2): 50-57.
  • Choi YS, Kim NK, Shim SH. Novel Single-nucleotide polymorphisms of SOHLH2 in Korean patients with premature ovarian failure. 발생과 생식. 2011;15(4):309- 313.
  • Park SY, Kim MH, An SA, Kim NK, Kim OJ, Oh SH. Analysis of an association between single nucleotide polymorphisms of vascular endothelial growth factor gene and risk of cerebral white matter lesion. J Korean Neurol Assoc 2012;30(3):182- 189.
  • Kwon SK, Kim JW, Kim NK. 5, 10-Methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and microsatellite instability (MSI) in sporadic colorectal cancer. Kor J Clin Oncol 2013;9:80-86.
  • Lee JW, Kim JW, Kim NK. Clinical characteristics of colorectal cancer patients with a second primary cancer. Ann Coloprotol 2014;30(1):18-22.
  • Kim JW, Jeon YJ, Jang MJ, Kim JO, Chong SY, Ko KH, Hwang SG, Oh D, Oh J, Kim NK. Association between folate metabolism-related polymorphisms and colorectal cancer risk in Koreans. Mol Clin Oncol 2015;3(3):639-648.

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