차 의과학대학교CHA University
 
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이성환

이성환 교수

전공외과, 간담췌외과, 시스템 생물학
연락처 leeshmd77@cha.ac.kr

학력

    박사 (연세대학교)

경력

  • Clinical Fellow, Department of HBP Surgery, Severance Hospital, Seoul, Korea
  • Research Fellow, Department of Pathology, Yonsei University College of Medicine
  • Postdoctoral Fellow, Department of Systems Biology, University of Texas MD Anderson Cancer Center, USA
  • Associate Professor, Department of Surgery, CHA University School of Medicine, Seongnam, Korea

논문

  • 7-1. Lee, S. H. et al (2024). Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial. Clinical and molecular hepatology, 30(4), 807. (IF=14.0)
  • 7-2. Lee, S. H. et al (2024). Differentially expressed genes associated with high metabolic tumor volume served as diagnostic markers and potential therapeutic targets for pancreatic cancer. Journal of Translational Medicine, 22(1), 453. (IF=6.1)
  • 7-3. Lee, S. H. et al (2023). Clinically conserved genomic subtypes of gastric adenocarcinoma. Molecular Cancer, https://doi.org/10.1186/s12943-023-01796-w (IF=37.3)
  • 7-4. Lee, S. H. et al (2023). High serum IL-6 correlated with reduced clinical benefit of atezolizumab and bevacizumab in unresectable hepatocellular carcinoma. JHEP Reports, 100672. (IF=8.3)
  • 7-5. Lee, S. H., Yim, S. Y., Jeong, Y. S., Li, Q. X., Kang, S. H., Sohn, B. H., ... & Lee, J. S. (2022). Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes. Hepatology, https://doi.org/10.1002/hep.32490 (IF=13.5)
  • 7-6. Lee, S. H., Jeong, Y. S., Lee, S., & Lee, J. S. (2022). Two distinct stem cell-like subtypes of hepatocellular carcinoma with clinical significance and their therapeutic potentials. Cancer communications, https://doi.org/10.1002/cac2.12251 (IF=16.2)
  • 7-7. Lee, S. H., Hwang, H. K., Lee, W. J., & Kang, C. M. (2021). MCT4 as a potential therapeutic target to augment gemcitabine chemosensitivity in resected pancreatic cancer. Cellular Oncology, 44(6), 1363-1371. (IF=6.6)
  • 7-8. Lee, S. H., Simoneau, E. B., Karpinets, T., Futreal, P. A., Zhang, J., Javle, M., ... & Chun, Y. S. (2021). Genomic profiling of multifocal intrahepatic cholangiocarcinoma reveals intraindividual concordance of genetic alterations. Carcinogenesis, 42(3), 436-441. (IF=4.7)
  • 7-9. Lee, S. H., Hwang, H. K., Lee, W. J., & Kang, C. M. (2019). Preoperative metabolic tumor volume2.5 associated with early systemic metastasis in resected pancreatic cancer: a transcriptome-wide analysis. Gut and liver, 13(3), 356. (IF=3.4)
  • 7-10. Lee, S. H., Park, S. A., Zou, Y., Seo, S. U., Jun, C. D., Lee, W. J., ... & Cho, N. H. (2018). Real-Time Monitoring of cancer cells in live Mouse Bone Marrow. Frontiers in immunology, 9, 1681. (IF=7.3)

저서/역서/편서

  • Molecular Subtypes and Genomic Signatures of Hepatocellular Carcinoma for Prognostication and Therapeutic Decision-Making (Humana Press)