황소현
황소현 교수
전공생명정보학
연락처
blissfulwin@cha.ac.kr
학력
- 공학박사
경력
- 2022년 3월 ~현재 차의과학대학교 의학전문대학원/분당차병원 병리과
- 부교수 2022년 11월 ~ 현재 대한종양내과학회 KOSMOS Molecular Tumor Board
- 분자종양위원회 위원 2016년 9월~ 2022년 2월 차의과학대학교 의생명과학과/분당차병원 병리과
- 조교수 2017년 1월~ 현재 한국생명정보학회 이사
- 재무위원장 (현재) 2015년 9월~2016년 8월 이화여자대학교 이화시스템생물학연구소
- 연구 교수 2012년 9월~2015년 8월 연세대학교 네트워크 생명공학연구실
- 연구 교수 2012년 9월~2015년 8월 Marcotte Lab., University of Texas at Austin(텍사스 주립대학교)
- 박사 후 연구원 2010년 3월~2012년 8월 연세대학교 네트워크 생명공학연구실
- 박사 후 연구원 2010년 6월~2012년 5월 AYRCOB (Asian Young researchers Conference on Computational and Omics Biology)
- 학회조직위원 (Review committee member) 2003년 9월~2007년 11월 생명공학연구원(KRIBB) 연구원
논문
- 7-1.J of Hepatology • Hwang S., Woo S., Kang B., Kang H., Kim J.S., Lee S.H., Kwon C.I., Kyung D.S., Kim H., Kim G., Kim C. and Chon H.J. Concordance of ctDNA and tissue genomic profiling in advanced biliary tractcancer. J of Hepatology, (published online), 2024.
- 7-2.Cell & Bioscience • Hwang S., Lim J., Kang H., Jeong J.Y., Jeong J.G., Heo J., Jung D., Cho, K. and An H. J. Predictive biomarkers for the responsiveness of recurrent glioblastomas to activated killer cell immunotherapy. Cell & Bioscience, 13 (1), 1-16, 2023.
- 7-3.Genes • Min Y., Park H.B., Baek K.H., and Hwang S. Cellular functions of deubiquitinating enzymes in ovarian adenocarcinoma. Genes, 14, 886, 2023.
- 7-4.Genes • Kim J.W., Kim S., Yang S.Y., Joung J.G. and Hwang S. T-cell receptor repertoire characteristics associated with prognostic significance in high-grade serous ovarian carcinoma. Genes, 14, 785, 2023.
- 7-5.J of Clin and Translational Hepatology • Sang Y. B., Kim G., Hwang S., Kang H. and Chon H. J. Dramatic response to carbozantibin in a patient with refractory hepatocellular carcinoma with c-MET amplification. Journal of Clinical and Translational Hepatology, 11 (3), 747-750, 2023.
- 7-6.Nature Biotechnology • Kwon J., Kang J., Jo A., Seo K., An D., Baykan M. Y., Lee J. H., Kim N. Eum H. H., Hwang S., Lee J. M., Park W. Y., An H. J., Lee H., Park J. and Choi J. K. Single cell mapping of combinatorial target antigens for CAR switches using logic gates. Nature Biotechnology. 1-13, 2023.
- 7-7.Genes • Kim S. and Hwang S. G-quadruplex matters in tissue-specific tumorigenesis by BRCA1 deficiency. Genes, 13, 391, 2022.
- 7-8.Cancers • Kang H., Choi M. C., Kim S., Jeong J., Kwon A., Kim T., Kim G., Joo W. D., Park H., Lee C., Song S. H., Jung S. G., Hwang S. (Co-corresponding) and An H. J. USP19 and RPL23 as candidate prognostic markers for advanced-stage high grades serous ovarian carcinoma. Cancers, 13, 3976, 2021.
- 7-9.Pharmaceuticals • Kim S. and Hwang S. Preclinical drug response metric based on cellular response phenotype provides better pharmacogenomic variables with phenotype relevance. Pharmaceuticals, 14, 1324, 2021.
- 7-10.J of Exp &Clin Cancer Res • Jung D, Baek Y. S., Lee I. J., Kim K. Y., Jang H., Hwang S., Jung J., Moon Y., Park K. Choi Y. and An H. J. Ex vivo expanded allogenic natural killer cells have potent cytolytic activity against cancer cells through different receptor-ligand interactions. Journal of Experimental & Clinical Cancer Research, 40 (1), 1-14, 2021.
- 7-11.Genes • Pandey K. Lee E., Park N., Hur J., Cho Y. B., Katuwal N. B., Kim S. K., Lee S. A., Kim I., An H. J. Hwang S. (Co-corresponding) and Moon Y. W. Deregulated immune pathway associated with palbociclib resistance in preclinical breast cancer models: integrative genomics and transcriptomics. Genes, 12, 159, 2021.
- 7-12.Cell • Lee J. S., Nair, N. U., Dinstag, G., Chapman L., Chung Y., Wang K., Sinha S., Cha H., Kim D., Schperberg A. V., Srinvisasan A., Lazar V., Rubin E., Hwang S., Berger R., Beker T., Ronal Z., Hannenhalli S., Gilbert M. R., Kurzrock R., Lee S. H., Aldape K., Ruppin E. Synthetic lethality-mediated precision oncology via the tumor transcriptome. Cell, 184, 1-16, 2021.
- 7-13.Scientific Reports • Hwang S., Kwan A., Jeong J., Kim S., Kang H., Park J., Kim J., Han O. J., Lim S. M. and An H. J. Immune gene signatures for predicting durable clinical benefit of anti-PD-1 immunotherapy in patients with non-small cell lung cancer, Scientific Reports, 10, 643, 2020.
- 7-14.Cancer Res Treat • Choi M.C. Hwang S. (Co-first), Kim S., Jung S. G., Park H., Joo W. D., Song S. H., Lee C., Kim T., Kang H. and An H. J. Clinical impact of somatic variants in homologous recombination repair-related genes in ovarian high-grade serous carcinoma. Cancer Res. Treat., 52, 2, 634-644, 2020.
- 7-15.Nucleic Acids Res. • Hwang S., Kim C.Y., Yang S., Kim E., Hart T., Marcotte E. M. and Lee I. HumanNet v2: human gene networks for disease research. Nucleic Acids Res., 8, 47, D573-D580, 2019.
- 7-16.Am J Resspir Crit Care Med • Yon D. K., Hwang S., Lee S. W., Jee H. M., Sheen Y. H., Kim J. H., Lim D. H., Han M. Y. Indoor exposure and sensitization to formaldehyde among inner-city children with increased risk of asthma and rhinitis.
- 7-17.Molecular Plant • Lee T., Hwang S. (Co-first), Kim C.Y., Shim H., Kim H., Ronald P. C., Marcotte E. M. and Lee I. WheatNet: a genome-scale functional network for hexaploid bread wheat, Triticum aestivum. Molecular Plant, 10: 1133-1136, 2017.
- 7-18.Scientific Reports • Hwang S., Kim C.Y., Ji S. G., Go J., Kim H., Yang S., Kim H.J., Cho A., Yoon S.S. and Lee I. Network-assisted investigation of virulence and antibiotic-resistance systems in Pseudomonas aeruginosa. Scientific Reports, 6: 26223, 2016.
- 7-19.Nucleic Acids Res. • Jo J., Hwang S. (Co-first), Kim H. J., Hong S., Lee J. E., Lee S., Baek A., Lee I. and Lee D. R. An integrated systems biology approach identifies positive cofactor 4 as a pluripotency regulatory factor. Nucleic Acids Res. 44 (3): 1203-1215, 2016.
- 7-20.Nucleic Acids Res. • Kim E, Hwang S, Kim H, Shim H, Kang B, Yang S, Shim J H, Shin S Y, Marcotte E M and Lee I. MouseNet v2: A database of gene networks for studying the laboratory mouse and eight other model vertebrates. Nucleic Acids Res. 44: D848-D854, 2016.
- 7-21.Scientific Reports • Hwang S., Kim E., Lee I. and Marcotte E. M. Systematic comparison of variant calling methods using gold standard personal exome variants. Scientific Reports, 5: 17875, 2015
- PLoS One • Shim J E, Hwang S, and Lee I. Pathway-dependent effectiveness of network algorithms for gene prioritization. PLoS One, 10(6): e0130589, 2015.
- 7-22.Nucleic Acids Res. • Hwang S, Kim E, Yang S, Marcotte E M, and Lee I. MORPHIN: a web tool for human disease research by projecting model organism biology onto a human integrated gene network. Nucleic Acids Res., 42: W147-W153, 2014.
- 7-23.GenomeBiol. • Wang P I, Hwang S (Co-first), Kincaid R P, Sullivan C S, Lee I and Marcotte E M. RIDDLE: Reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network. Genome Biol., 13:R125, 2012.
- 7-24.Nat Protocols • Hwang S, Rhee S Y, Marcotte E M, and Lee I. Systematic prediction of candidate gene function associated to phenotype traits using the probabilistic functional gene network of Arabidopsis thaliana. Nature Protocols, 6:1429, 2011.
- 7-25.BMC Bioinformatics • Hwang S, Kim S, Shin H, Lee D. Context-dependent transcriptional regulations between signal transduction pathways. BMC Bioinformatics, 12:19, 2011.