[연구내용]
나노바이오기술은 차세대 핵심기술 중 가장 각광 받고 있는 분야이며, 그 중 나노바오센서/나노바이오칩 기술은 다양한 질병 조기진단 및 식품과 환경 모니터링, 효과적 세포 연구 분야에 응용 가능함.
- 질병 조기진단용 광학 및 전기화학 나노바이오센서
- 신약독성 평가 및 줄기세포 분화 연구를 위한 생체모방칩 혹은 Organ-on-a-chip
- 불임 연구용 생체모방칩
- 유전공학 기술에 의한 새로운 바이오물질 개발과 이의 바이오센싱 시스템으로의 응용
- 식품위해물질 신속검출 및 식품공정 모니터링 바이오센서
- 환경 모니터링 바이오센서
[논문]
최근 5년간
- Rapid detection of aflabtoxin B1 by a bifunctional protein crosslinker-based surface plasmon resonance biosensor. 2014. Food Control. 36(1), 183-190 .(Corresponding author)
- Colorimetric assay of matrix metalloproteinase activity based on metal-induced self-assembly of carboxy gold nanoparticles. 2013. Biosensors and Bioelectronics. 41: 833-839.(Corresponding author)
- Reversible creation of nanostructures between identical or different species of materials. 2012. Applied Physics A. 108(1):41-52. (First author)
- Preparation and application of 3C-SiC substrate to piezoelectric micro cantilever transducers. 2012. Applied Physics A. 108(1):161-170. (Corresponding author)
- Effect of nanoliposomes on the stabilization of incorporated retinol. 2010. African Journal of Biotechnology. 9: 6158-6161 (First author)
- Immobilization of genetically engineered fusion proteins on gold-decorated carbon nanotube hybrid films for the fabrication of biosensor platforms. 2010. Journal of Colloid and Interface Science. 350:453-458 (Co-author)
- Fabrication of anionic sulfate-functionalized nanoparticles as an immunosensor by protein immobilization. 2010. Langmuir. 26:7355-7364 (Co-author)
- A self-assembled fusion protein-based surface plasmon resonance biosensor for rapid diagnosis of sever acute respiratory syndrome. 2009. Talanta. 79: 295-301 (Corresponding author)
- Directed self-assembly of gold binding polypeptide-protein A fusion proteins for development of gold nanoparticle-based SPR immunosensor. 2009. Biosensors and Bioelectronics. 24(8): 2592-2597 (First and corresponding author)
- Energy transfer-based multiplexed assay of proteases by using gold nanoparticle and quantum dot conjugates on a surface. 2008. Analytical Chemistry. 80(12): 4634-4641 (Co-author)
- An active mixing microfluidic system for the colorimetric analysis of intracellular enzymes. 2008. Biochip Journal. 2(1): 33-38 (Co-author)
- Preparation of nano-liposome by sonication and pressure. 2008. Korean J. Food Sci. Technol. 40(1): 115-117 (Co-author)
- Production technology of food nanoemulsions and its application in food industry. 2007. Food Engineering Progress. 11:237-247 (Co-author)
- Electrochemical detection of cardiac troponin I using a microchip with the surface-functionalized poly(dimethylsiloxane) channel. 2007. Biosensors & Bioelectronics. 23(1):51-59 (First author)
- Protein nanopatterns and biosensors using gold binding polypeptide as a fusion partner. 2006. Analytical Chemistry. 78:7197-7205 (Co-author)
- A novel FRET-based optical fiber biosensor for rapid detection of Salmonella Typhimurium. 2006. Biosensors & Bioelectronics. 21:1283-1290 (First author)