임지혜

임지혜 교수

전공의학유전학

연락처 031-780-6020 limjh3377@chamc.co.kr

학력

1997 - 2001 한양대학교 이과대학 생화학 분자생물학과(이학학사)
2001 - 2003 고려대학교 대학원 의과대학-분자세포 발생생물학(의학석사)
2017 - 2019 한양대학교 대학원 의과학과-의학유전학(이학박사)

경력

2000 ~ 2003 고려대학교 임상의학연구소
2003 ~ 2006 이화여자대학교 뇌신경과학연구소
2006 ~ 2018 제일병원 의학연구소 유전학연구실
2022 ~ 현재 차그룹 미래의학연구원 / 스마트 MEC케어 R&D연구센터 / 모체태아의학연구팀 / 팀장 (수석연구원)
2022 ~ 현재, IRIS 국책연구분야 평가위원
2023 ~ 현재, 대한의학유전학회 산학협력위원회 위원

논문

Lim JH, Kim SY, Park SY, Yang JH, Kim MY, Ryu HM. Effective prediction of preeclampsia by a combined ratio of angiogenesis-related factors. Obstet Gynecol. 2008 Jun;111(6):1403-9. doi: 10.1097/AOG.0b013e3181719b7a. PMID: 18515525
Lim JH, Lim JM, Lee HM, Lee HJ, Kwak DW, Han YJ, Kim MY, Jung SH, Kim YR, Ryu HM, Kim KP. Systematic Proteome Profiling of Maternal Plasma for Development of Preeclampsia Biomarkers. Mol Cell Proteomics. 2024 Sep;23(9):100826. doi: 10.1016/j.mcpro.2024.100826. PMID: 39111712
Lim JH, Lee DE, Kim KS, Kim HJ, Lee BY, Park SY, Ahn HK, Lee SW, Kim MY, Ryu HM. Non-invasive detection of fetal trisomy 21 using fetal epigenetic biomarkers with a high CpG density. Clin Chem Lab Med. 2014 May;52(5):641-7. doi: 10.1515/cclm-2013-0802. PMID: 24353143
Lim JH, Kang YJ, Bak HJ, Kim MS, Lee HJ, Kwak DW, Han YJ, Kim MY, Boo H, Kim SY, Ryu HM. Epigenome-wide DNA methylation profiling of preeclamptic placenta according to severe features. Clin Epigenetics. 2020 Aug 24;12(1):128. doi: 10.1186/s13148-020-00918-1. PMID: 32831145
Lim JH, Kang YJ, Lee BY, Han YJ, Chung JH, Kim MY, Kim MH, Kim JW, Cho YH, Ryu HM. Epigenome-wide base-resolution profiling of DNA methylation in chorionic villi of fetuses with Down syndrome by methyl-capture sequencing. Clin Epigenetics. 2019 Dec 4;11(1):180. doi: 10.1186/s13148-019-0756-4. PMID: 31801612
Lim JH, Lee JC, Lee YH, Choi IY, Oh YK, Kim HS, Park JS, Kim WK. Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal. J Neurochem. 2006 Apr;97(1):140-50. doi: 10.1111/j.1471-4159.2006.03715.x. PMID: 16515553
Choi IY, Lim JH, Kim C, Song HY, Ju C, Kim WK. 4-hydroxy-2(E)-Nonenal facilitates NMDA-Induced Neurotoxicity via Triggering Mitochondrial Permeability Transition Pore Opening and Mitochondrial Calcium Overload. Exp Neurobiol. 2013 Sep;22(3):200-7. doi: 10.5607/en.2013.22.3.200. PMID: 24167414
Lim JH, Park SY, Kim SY, Kim DJ, Choi JE, Kim MH, Choi JS, Kim MY, Yang JH, Ryu HM. Effective detection of fetal sex using circulating fetal DNA in first-trimester maternal plasma. FASEB J. 2012 Jan;26(1):250-8. doi: 10.1096/fj.11-191429. PMID: 21965598
Lim JH, Han YJ, Kim HJ, Kwak DW, Park SY, Chun SH, Ryu HM. Genome-wide gene expression analysis in the placenta from fetus with trisomy 21. BMC Genomics. 2017 Sep 12;18(1):720. doi: 10.1186/s12864-017-3993-y. PMID: 28899343
Lee DE, Lim JH, Kim MH, Park SY, Ryu HM. Novel Epigenetic Markers on Chromosome 21 for Noninvasive Prenatal Testing of Fetal Trisomy 21. J Mol Diagn. 2016 May;18(3):378-387. doi: 10.1016/j.jmoldx.2015.12.002. PMID: 26947512

저서/역서/편서

2012 / 공동저자 / 유전성 유방암 / 2012-03 / 공동저자 / 군자출판사
2016 / 공동저자 / 모태독성학 / 2016-08 / 공동저자 / 군자출판사
2022 / 공동저자 / 모대독성학 / 2022-10 / 공동저자 / 군자출판사